calcitriol

(redirected from 1,25-dihydroxycholecalciferol)
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calcitriol

[‚kal·sə′trī‚ōl]
(biochemistry)
1,25-dihydroxycholecalciferol, the form of vitamin D that is involved in intestinal absorption of Ca2+and Ca2+resorption by bone.
References in periodicals archive ?
Role of 1,25-dihydroxycholecalciferol in calcification of bone and maintenance of serum calcium concentration in the rat.
Effects of ascorbic acid and 1,25-dihydroxycholecalciferol on alkaline phosphatase and tibial dyschondroplasia in broiler chickens.
1-hydroxylase found primarily in the kidney resulting in the formation of 1,25-dihydroxycholecalciferol.
Cholecalciferol is hydroxylated to 25-hydroxycholecalciferol in the liver; 25-hydroxycholecalciferol is then transformed by the kidneys to the hormonally active metabolite calcitriol, 1,25-dihydroxycholecalciferol (1,25-[(OH).
1,25-Dihydroxycholecalciferol inhibits the progression of arthritis in murine models of human arthritis.
Interactions of parathyroid hormone, 25-hydroxycholecalciferol, and 1,25-dihydroxycholecalciferol.
Kulturun yedinci gununde olgunlasan noronlar uc gruba bolundu: Vitamin D uygulanan grup; yedinci gun, 24 ve 48 saat sureyle etanol icinde cozundurulen 10-8 M 1,25 dihidroksivitamin D3 (calcitriol, 1,25-dihydroxycholecalciferol, Sigma C-9756.
The enzyme 1a-hydroxylase, which activates vitamin D to 1,25-dihydroxycholecalciferol, is also stimulated, which results in increased Ca absorption from the intestines (Costanzo, 2006), because 1,25-dihydroxycholecalciferol may enhance the synthesis of calcium binding proteins (Kumar, 1995) and calcium channels in the enterocyte (Bouillon et al.
Correction of enhanced Na(+)-H+ exchange of rat small intestinal brush-border membranes in streptozotocin-induced diabetes by insulin or 1,25-dihydroxycholecalciferol.
After isomerisation of previtamin D in the skin, 25-hydroxylation in the liver and 1[alpha]-hydroxylation in the kidney, the active form 1,25-dihydroxycholecalciferol may exert the beneficial effects in the prevention and treatment of several diseases, namely in rickets, osteomalacia and osteoporosis.
The effects of 1,25-dihydroxycholecalciferol and phytase on the natural phytate phosphorus utilization by laying hens.