calcitriol

(redirected from 1,25-dihydroxycholecalciferol)
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calcitriol

[‚kal·sə′trī‚ōl]
(biochemistry)
1,25-dihydroxycholecalciferol, the form of vitamin D that is involved in intestinal absorption of Ca2+and Ca2+resorption by bone.
References in periodicals archive ?
The Influence of vitamin A on the utilization and amelioration of toxicity of cholecalciferol, 25 hydroxycholecalciferol, and 1,25-dihydroxycholecalciferol in young broilerchickens.
1,25-Dihydroxycholecalciferol and the genesis of hypocalcaemia in magnesium-deficient chicks.
1,25-Dihydroxycholecalciferol supplementation prevents hypocalcaemia in magnesium-deficient chicks.
As renal mass dwindles and phosphate excretion gets more difficult, synthesis of 1,25-dihydroxycholecalciferol is impaired, and concentrations of fibroblast growth factor-23 increase (2), leading to low serum calcium concentrations and an initially appropriate response of the parathyroids: parathyroid hormone (PTH) synthesis increases.
Accordingly, in birds, it was postulated that ascorbic acid stimulates 1,25-dihydroxycholecalciferol and together these compounds increase calcium mobilization from bones, suggesting that vitamin C has an important role in egg shell formation (Sahin and Sahin, 2001).
Decreased free 1,25-dihydroxycholecalciferol index in patients with the nephrotic syndrome.
Ascorbic acid may influence bone development by mediating the biosynthesis of 1,25-dihydroxycholecalciferol and collagen (Farquharson and Jefferies, 2000; McCormack et al.
Apart from mechanical forces, bone remodeling is regulated by systemic hormones, including parathyroid hormone (PTH) and 1,25-dihydroxycholecalciferol (calcitriol).