Deoxycorticosterone

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deoxycorticosterone

[dē¦äk·sē‚kȯrd·ə′kä·stə‚rōn]
(biochemistry)
C21H30O3 A steroid hormone secreted in small amounts by the adrenal cortex.

Deoxycorticosterone

 

(also cortexone), an intermediate product in the biosynthesis of hormones of the adrenal cortex. Formed primarily from progesterone, it is a mineralocorticoid, that is, an active regulator of mineral metabolism, and in this connection the most stable preparation of deoxycorticosterone is deoxycorticosterone acetate, which is used in medicine.

References in periodicals archive ?
Corticosterone, 11-deoxycorticosterone, and aldosterone concentrations in the medium were measured with HPLC using UV detection (241 nm).
We have tentatively identified 11-deoxycorticosterone, androstadienedione, and androstenedione in the effluent.
Simultaneous radioimmunoassay of plasma aldosterone, corticosterone, 11-deoxycorticosterone, progesterone, 17-hydroxyprogesterone, 11-deoxycortisol, cortisol and cortisone.
Deficiency in the CYP21 gene prevents the conversion of 17-hydroxyprogesterone to 11-deoxycorticosterone, leading to an excessive production of androgen, which in turn affects several stages of growth and development (1).