two-dimensional gel electrophoresis

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two-dimensional gel electrophoresis

[¦tü·də‚men·shən·əl ¦jel i‚lek·trō·fə′rē·səs]
(cell and molecular biology)
A type of gel electrophoresis in which proteins are first separated by charge and then by molecular weight, enabling the analysis of complex protein mixtures.
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I think that's where Bio-Rad can really make a difference because we're already strong in chromatography and sample preparation, and we're the market leader, for example, in 2-D electrophoresis," Dr.
Also, the joint research group has successfully reduced in size the new system to a quarter the conventional 2-D electrophoresis system.
Nasdaq: GNSL), a leading, worldwide supplier of automated solutions for genomic and proteomic research, has introduced Investigator(TM) High Throughput 2-D electrophoresis analysis PC software.
After incubation, the samples were mixed with Urea Mix for 2-D electrophoresis analysis, or with SDS Mix for 1-D analysis.
Establishing a proteomics platform in the industrial setting initially requires implementation of a series of robotic systems to allow a high-throughput approach for analysis and identification of differences observed on 2-D electrophoresis gels.
Bio Image was previously focused on image analysis software for 2-D electrophoresis and high-density grids.
Ettan(TM) DIGE technology from Amersham Biosciences has significant benefits over classic 2-D electrophoresis, providing a very sensitive and accurate method for measuring differences in protein expression.
Many biotech joint alliances have been aimed at combining technologies to produce integrated systems such as GSI and ESA's automated 2-D electrophoresis system.
Newly updated 2-D electrophoresis gel image analysis software available from Amersham Biosciences, the life sciences company of Amersham (LSE:, NYSE:, OSE: AHM), is to help address critical bottlenecks of image analysis in proteomics research.
The MALDI-TOF is excellent for this analysis because of its speed and the way it can use the samples from the 2-D electrophoresis.
These HT Analyzer products will be integrated into the Investigator(TM) proteomics line offered by Genomic Solutions, which includes a 2-D electrophoresis system, ProPic(TM) robotic workstation, ProGest(TM) protein digestion station, ProMS(TM) MALDI preparation station and ProPrep(TM) protein digestion and mass spec preparation station.
Ettan DIGE is a unique system that brings an as yet unrivalled statistical confidence and level of reliability to 2-D electrophoresis results, as each protein spot has its own internal standard.