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hydroxylase |
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hydroxylase [hī′dräk·sə‚lās] (biochemistry) Any of several enzymes that catalyze certain hydroxylation reactions involving atomic oxygen. How to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit webmaster's page for free fun content. |
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| ? Mentioned in | ? References in periodicals archive | |
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The most common type of
CAH is 21-hydroxylase deficiency, within which three severity subtypes
are distinguished: Saltwasters (SW), the most severe subtype, in which
the enzyme deficiency causes deficiencies of both glucocorticoid
(glucose-regulating) and mineralocorticoid (sodium-regulating) hormones;
simple virilizers (SV), with moderate deficiencies of glucocorticoids;
and the mildest subtype, non-classical (NC), late-onset CAH. I focused on the most
prevalent intersex syndrome, classical (prenatal-onset) congenital
adrenal hyperplasia (CAH) due to 21-hydroxylase deficiency, and
summarized recent psychological research in children and adults with
this syndrome, complemented by studies on intersex syndromes in 46, XY
individuals. Amniotic fluid concentrations of
delta-5 and delta-4 steroids in fetuses with congenital adrenal
hyperplasia due to 21-hydroxylase deficiency and in anencephalic
fetuses. |
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