5-FU


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5-FU

(pharmacology)
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Although commonly seen with 5-FU infusion cardiotoxicity can occur with IV bolus also.
Small sample size taken in different comparative studies of intralesional 5-FU and TCA done abroad ranged from 28-30 cases.
The greater efficacy of calcipotriol plus 5-FU versus Vaseline plus 5-FU treatment in eliminating actinic keratoses remained highly significant after controlling for the baseline actinic keratosis count, age, and sex of the participants," they wrote (J Clin Invest.
On the right upper arm, the dual regimen removed 70% of AKs, compared with 10% for monotherapy, and on the left upper arm, combination treatment removed 80% of AKs, while 5-FU alone removed only 16% (all P values for these differences were less than .
A total dose of around 1ml of 5-FU (10mg/ml) injected into the lesion depending upon the size of keloid once in 2 weeks for a period of 3 months with a dose of around 0.
As one of the antimetabolites that interfere with DNA production, 5-FU interferes with cell proliferation.
The effects of 5-FU and SBE on growth of Bel-7402, HCT-8 and L02 cells were evaluated by 3-(4,5-dimethylthiazol-2-yl)-5-(3-carboxymethoxyphenyl)-2-(4-sulfophenyl)-2H-tetrazolium (MTS)/phenazine methosulfate (PMS) assay.
Pearson\'s Correlation coefficient was calculated to see any possible correlation between 5-FU alone and 5-FU based regimens and cardiotoxicity, and other variables.
Discontinuation of 5-FU infusion and immediate administration of sublingual nitrate is the life saving first line of therapy in the treatment of cardiovascular complications of 5-FU.
Continuous infusion 5-FU as a first-line therapy for metastatic breast cancer has moderate activity and low toxicity.
peruviana ethanolic leave and stem extracts, and 5-FU was used as positive control.
Taken orally, capecitabine is converted by the body into 5-FU.