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5-Hydroxytryptophan

   Also found in: Medical, Wikipedia 0.01 sec.
5-hydroxytryptophan [¦fīv hī¦dräk·sē′trip·tə‚fan]
(biochemistry)
C11H12N2O3Minute rods or needlelike crystals; the biological precursor of serotonin.

5-Hydroxytryptophan 

(also β-5-hydroxyindolyl-3-alanine), an amino acid. Two optically active forms and one racemic form exist for 5-hydroxytryptophan. In animals and man, L-5-hydroxytryptophan is produced as a result of the enzymatic hydroxylation of L-tryptophan during the conversion of L-tryp-tophan into the nervous-system mediator serotonin. When injected parenterally, 5-hydroxytryptophan has a hallucinogenic effect.



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5-Hydroxytryptophan or simply 5-htp is another common OTC diet drug.
This effect of intraluminal application of 5-hydroxytryptamine and 5-hydroxytryptophan on peristalsis, the local production of 5-hydroxytryptamine and its release in relation to intraluminal pressure and propulsive activity.
However, tryptophan and its metabolite 5-hydroxytryptophan (5-HTP), from which serotonin is synthesized, can and do cross the blood-brain barrier.
 
 
 
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