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fluorouracil
(redirected from 5-fluorouracil)

    Also found in: Dictionary/thesaurus, Medical, Acronyms, Wikipedia 0.03 sec.
fluorouracil: see metabolite metabolite, organic compound that is a starting material in, an intermediate in, or an end product of metabolism. Starting materials are substances, usually small and of simple structure, absorbed by the organism as food.
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fluorouracil [¦flu̇r·ō′yu̇r·ə‚sil]
(pharmacology)
C4H3FN2O2Crystals that decompose at 282-283°C; used as an antineoplastic drug and as an inhibitor of deoxyribonucleic acid synthesis. Also known as 2,4-dioxo-5-fluoropyrimidine; 5-FU.
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Manuskiatti and Fitzpatrick (2002) compared scar treatment with intralesional corticosteroids alone or combined with 5-fluorouracil or 5-fluorouracil alone or the pulsed dye laser using fluences of 5 Jcm-2.
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During the study, the researchers reported that two genes - astrocyte elevated gene-1, or AEG-1, and late SV40 factor, LSF, contribute to resistance of a commonly used chemotherapeutic drug called 5-fluorouracil, or 5-FU.
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Capecitabine plus oxaliplatin (XELOX) versus 5-fluorouracil plus oxaliplatin (FOLFOX4) plus bevacizumab or placebo as first-line therapy in metastatic colorectal cancer: A randomised non inferiority phase III study.
Anti-epidermal growth factor receptor monoclonal antibodies ... by Ruiz-Echarri, Manuel; Ramos, Francisco Javier; Macarulla, Teresa; Capdevila, Jaume; Elez, Elena; Tab / Advances in Gastrointestinal Cancer
 
 
 
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