5-Hydroxytryptophan

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5-hydroxytryptophan

[¦fīv hī¦dräk·sē′trip·tə‚fan]
(biochemistry)
C11H12N2O3 Minute rods or needlelike crystals; the biological precursor of serotonin.

5-Hydroxytryptophan

 

(also β-5-hydroxyindolyl-3-alanine), an amino acid. Two optically active forms and one racemic form exist for 5-hydroxytryptophan. In animals and man, L-5-hydroxytryptophan is produced as a result of the enzymatic hydroxylation of L-tryptophan during the conversion of L-tryp-tophan into the nervous-system mediator serotonin. When injected parenterally, 5-hydroxytryptophan has a hallucinogenic effect.

References in periodicals archive ?
However, a small number of people actually have trouble sleeping from 5-HTP, and should then take it early in the day.
He also noted that taking 5-HTP has dramatically reduced his post-E depression.
Treatment with 2 mM 5-HTP caused a massive increase in 5-HTP concentration that was observable immediately after the 30-min exposure period (Fig.
Patients who take 5-HTP (5-hydroxytryptophan) as an antidepressant, as a sleep aid, or for weight loss or other complaints may be at risk for developing the syndrome.
HPLC-grade acetonitrile was obtained from Rathburn; serotonin creatine sulfate, ascorbic acid, and potassium dihydrogen phosphate were from Merck; 5-HTP, tryptophan, and 5-HIAA were from Sigma Chemical Co.
In addition, 5-HTP may increase the hormone serotonin and reduce hunger pangs, and chromium picolinate may promote the loss of fat rather than lean tissue.
A carboline compound derivative of 5-HTP kills garden or field slugs and does not appear to affect plants.
Nutritional supplements - the following vitamins have been shown to aid in combating stress: vitamin C, magnesium citrate, B-complex, GABA, 5-HTP, green tea, phosphatidyl serine and amino acid complex.
5-HTP (5-Hydroxtryptophan) supports the serotonin pathways.
Supporting the merchandising has been educational signage, such as that discussing enzyme CoQ10 in the cardiovascular set or the material in the sleep set on melatonin, 5-HTP and valerian.
A deficiency of 5-HTP can cause serotonin imbalances which are associated with high glycemic food cravings.