5-Hydroxytryptophan

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5-hydroxytryptophan

[¦fīv hī¦dräk·sē′trip·tə‚fan]
(biochemistry)
C11H12N2O3 Minute rods or needlelike crystals; the biological precursor of serotonin.

5-Hydroxytryptophan

 

(also β-5-hydroxyindolyl-3-alanine), an amino acid. Two optically active forms and one racemic form exist for 5-hydroxytryptophan. In animals and man, L-5-hydroxytryptophan is produced as a result of the enzymatic hydroxylation of L-tryptophan during the conversion of L-tryp-tophan into the nervous-system mediator serotonin. When injected parenterally, 5-hydroxytryptophan has a hallucinogenic effect.

References in periodicals archive ?
3] Nonstandard abbreviations: 5-HIAA, 5-hydroxyindoleacetic acid; 5-HTP, 5-hydroxytryptophan; AUC, area under the curve; NPV, negative predictive value; and PPV, positive predictive value.
5-HTP is converted to serotonin by the decarboxylase enzyme, which is vitamin-B6 dependent.
Recently, it has been demonstrated that 5-HTP (3-200 mg/kg i.
The winning supplements -- chosen by a roster of experts, consumers, and Better Nutrition editors -- will be featured in the magazine's November '09 issue, recognizing over 70 outstanding products in more than 30 categories, including Natrol([R]) 5-HTP, winner of the "Brain and Wellness" category.
The present study showed that pretreatment of FAN (IP) inhibited morphine (SC)-induced antinociception significantly in the tail-flick test, but not in the tail-pinch tests carried out in mice, and that this antagonistic effect was abolished by pretreatment with 5-HTP, a serotonin precursor, but not by pretreatment with a noradrenaline precursor, L-DOPA, in the tail-flick test.
For example, if you give 5-HTP to manufacture serotonin, it inhibits the conversion of tyrosine to dopamine, norepinephrine, and epinephrine; and vice versa: giving only tyrosine will impede serotonin formation.
5 Patrick Holford Mood Food, 60 capsules, from Holland & Barrett This mega multi-vit includes tyrosine, 5-HTP and B vitamins, which has been shown to support production of 'feel-good' chemicals.
New Natrol Product Features Effective Ingredients, Including 5-HTP For Anti-Anxiety, And Melatonin To Help Consumers Fall Asleep Fast And Stay Asleep All Night (+)
The dosage of 5-HTP was 50 mg 3 times per day for 2 weeks, then 100 mg 3 times per day for 2 weeks, then 400 mg per day in 3 divided doses per day.
Symposium guest speakers include Ward Dean, MD, author of Biological Aging Measurements and Smart Drugs & Nutrients; Terry Grossman, MD, co-author of Fantastic Voyage and Transcend, (Nine Steps to Living Well Forever) with Ray Kurzweil; Richard Kaufman, PhD, author of the Age Reduction System; Will Block, publisher of Life Enhancement magazine, and author of The 5-HTP Archives; Bill Andrews, PhD, leader of the team at Geron Corporation to first identify human telomerase, and now head of Sierra Sciences, a company that has screened for a natural substance that slows down or stops the telomere aging clock.
45 for 60 capsules, from Holland & Barrett This mega multi-vit includes tyrosine, 5-HTP and B vitamins, which has been shown to support production of 'feel-good' chemicals.