ACE inhibitor

(redirected from Acei)
Also found in: Dictionary, Thesaurus, Medical, Acronyms.
Related to Acei: Beta blockers, Calcium channel blockers, AECI

ACE inhibitor

(ā'sē'ē`, ās) or

angiotensin-converting enzyme inhibitor

(ăn'jēōtĕn`sĭn), drug used to reduce elevated blood pressure (see hypertensionhypertension
or high blood pressure,
elevated blood pressure resulting from an increase in the amount of blood pumped by the heart or from increased resistance to the flow of blood through the small arterial blood vessels (arterioles).
..... Click the link for more information.
), to treat congestive heart failurecongestive heart failure,
inability of the heart to expel sufficient blood to keep pace with the metabolic demands of the body. In the healthy individual the heart can tolerate large increases of workload for a considerable length of time.
..... Click the link for more information.
, and to alleviate strain on hearts damaged as a result of a heart attack (see infarctioninfarction,
blockage of blood circulation to a localized area or organ of the body resulting in tissue death. Infarctions commonly occur in the spleen, kidney, lungs, brain, and heart.
..... Click the link for more information.
). ACE inhibitors block production of an enzyme that helps convert the protein angiotensin 1 into angiotensin 2, a protein that makes blood vessels constrict and promotes retention of fluid, raising blood pressure. Thus ACE inhibitors act to widen the blood vessels and make it easier for the heart to pump blood through the body. captopril (Capoten), ramipril (Altace), and enalapril (Vasotec) are commonly used ACE inhibitors. Angiotensin-receptor blockers (ARBs), such as losartan (Cozaar) and valsartan (Diovan), reduce hypertension by displacing angiotensin 2 from receptors on the surface of cells. ARBs are used as alternatives to the less expensive ACE inhibitors because they have fewer side effects.
References in periodicals archive ?
Additionally, on January 23, 2001 ACEI announced a stock repurchase program, in which management clearly indicated their belief that ACEI stock was undervalued.
Much of her work with ACEI has been on an international initiative to improve the quality of inclusive early child care and education.
Hazel B McCanne-TSU ACEI (coadvisers, Laura Duhon and Dianne Pape) Eagles Educate ACEI (adviser, Tunde Szecsi).
To maintain the professional stature we need in the world today, it is critical that ACEI elects the most highly competent and committed Executive Board members.
King adds, "The evolution of entertainment, occurring as a result of the Internet and related enabling technologies, provides significant business opportunities for ACEI.
The 2011 ACEI conference is just a few months away; attending the conference can be a life-changing experience for many in gaining new perspectives and meeting like-minded professionals in the field.
The award is presented during the ACEI Annual Conference, and the winning adviser will receive a commemorative plaque and a one-year ACEI professional membership.
I hope that these WISE events and similar initiatives will provide opportunities for ACEI to join with the global education community in efforts to address major educational challenges in innovative ways and to collaborate on developing the tools and strategies neceesary for sustainable solutions.
ACEI is pleased to introduce Mindi Batson as the Program Development Specialist on Headquarters staff.
Congratulations to the following 2009 recipients of the ACEI Chapter Excellence Award:
To make it easy for you to participate, ACEI Headquarters has developed a new resource--e-mail templates you can personalize and send to encourage your colleagues and friends to join ACEI.
ACEI is pleased to announce the election of Debora Wisneski to the position of President-Elect.