Summary: A simple and improved protocol for the a-monobromination of acetophenone and acetyl carbazole derivatives using different ammonium hydrotribromide salts under mild reaction condition was described.
Five acetophenone derivatives (1a-e) beside 3,6- diacetyl-9-ethyl carbazole (1f) were brominated by different ammonium hydrotribromide (I-VI) and bromo derivatives (2a-f) were obtained in good yields (Scheme 1).
Physical data of iodo hydroxy acetophenones
Entry Substrate Product M.
A set of four E-3 arylidene flavanones were synthesized by simple base catalysed condensation of appropriate aryl aldehydes and 2'4'dihydroxy acetophenone.
Keywords: Analgesic activity, Anti-oxidant activity, E-3arylidene flavanone, 2'4'dihydroxy acetophenone.
The same is true for the triplet state of [Alpha]-morpholino para methyl thioketones (16) or para methyl thiobenzophenones (17) or of para methyl thiosulfonyl acetophenones
(10) where a broad T - T absorption with a maximum at 490 nm is recorded before the [Beta] cleavage process which occurs in the microsecond time scale.
The acylhydrazide Schiff bases were synthesized by refluxing in ethanol a mixture 2 mmol of acyhydrazine with 2 mmol of different aldehyde or acetophenone
and catalytical amount of acetic acid for 3 h.
16] developed a set of fifty nine chalcones (especially methoxylated and some hydroxylated derivatives) by Claisen-Schmidt condensation of required acetophenone
with various substituted benzaldehydes.
Condensation between compound III and substituted acetophenones
The synthesized new substituted [beta]-diketone (3a-c) as well as substituted 2-hydroxy acetophenone
(1) and 2-benzoyloxy acetophenones
(2a-c) were not yet been studied for antimicrobial activities.
Noteworthy is also the detection of 4,6-dihydroxyacetophenone 2-O-[beta]-D-glucopyranoside in that acetophenones
being reported to occur only in a limited number of plant families (Singh et al.
Chalcones are products of condensation of simple or substituted aromatic with simple or substituted acetophenones
in presence of alkali.