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acetylcholine receptor

   Also found in: Medical, Acronyms, Wikipedia 0.04 sec.
acetylcholine receptor [ə‚sed·əl ′kō‚lēn ri‚sep·tər]
(cell and molecular biology)
A receptor in the membranes of certain cell structures, such as synapses or the neuromuscular junction, to which the transmitter substance acetylcholine binds. Nicotinic acetylcholine receptors are gated ion channels that open in response to acetylcholine, leading to an increase in membrane conductance; muscarinic acetylcholine receptors are G-protein-linked receptors inducing membrane ion channel changes or intracellular processes such as smooth muscle contraction.


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The research on insect nicotinic acetylcholine receptors reported by Dr.
2]-muscarinic acetylcholine receptor down-regulation, as would have occurred with chronic cholinergic hyperstimulation.
3] Receptor Channel," "Mechanisms of Activation of Muscle Nicotinic Acetylcholine Receptors and the Time Course of Endplate Currents, " "Mechanisms of Activation of Glutamate Receptors and the Time Course of Excitatory Synaptic Currents" and "Physiological Diversity of Nicotinic Acetylcholine Receptors Expressed by Vertebrate Neurons.
 
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