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acetylcholine receptor
(redirected from Acetylcholine receptors)

   Also found in: Dictionary/thesaurus, Medical, Wikipedia 0.01 sec.
acetylcholine receptor [ə‚sed·əl ′kō‚lēn ri‚sep·tər]
(cell and molecular biology)
A receptor in the membranes of certain cell structures, such as synapses or the neuromuscular junction, to which the transmitter substance acetylcholine binds. Nicotinic acetylcholine receptors are gated ion channels that open in response to acetylcholine, leading to an increase in membrane conductance; muscarinic acetylcholine receptors are G-protein-linked receptors inducing membrane ion channel changes or intracellular processes such as smooth muscle contraction.


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Previous studies have shown that an antagonist of nicotine acetylcholine receptors (nAChRs), called d-tubocurarine/a-Cobratoxin (a-CbT), may serve as an anticancer agent because it specifically targeted the a7 subunit of nAChRs, the area primarily associated with increased cell proliferation.
Although relatively rare, this is a serious condition in which acetylcholine receptors are deactivated on muscle cells.
Whether the molecule in its current form binds too many types of acetylcholine receptors, whether it activates other neurological systems or whether suicide risk is simply elevated among people giving up cigarettes is unknown.
 
 
 
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