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A condition of decreased alkali reserve of the blood and other body fluids.



a change in the acid-alkaline balance of the organism as a result of insufficient removal and oxidation of organic acids (for example, beta-hydroxybutyric acid). Usually these products are rapidly removed from the body. In febrile diseases, intestinal disorders, pregnancy, starvation, and such, they are retained in the body; this is manifested in mild cases by the appearance of acetoacetic acid and acetone in the urine (so-called ketonuria). In severe cases (for example, diabetes mellitus) it may lead to coma. Treatment consists of removal of the cause of acidosis (for example, by administering insulin in case of diabetes); there is also symptomatic treatment—soda and an abundance of fluids taken internally.

References in periodicals archive ?
The presence of metabolic acidaemia or low bicarbonate is of additional value to the Apgar score in predicting poor outcome, as the Apgar score is often not done in real time and can therefore be unreliable.
METHYLMALONIC acidaemia (MMA) is a disorder which means the body is unable to process certain proteins and fats properly.
Glutaric acidaemia type 1 - GA1, isovaleric acidaemia and long chain fatty acidaemia are metabolic conditions which each affect one in 100,000 children.
5) However, if acidaemia is severe, the AG may actually drop by up to 4 mmol/l as a result of an increment in the net cationic charge of proteins.
Neurological dysfunction in methylmalonic acidaemia is probably related to the inhibitory effect of methylmalonate on brain energy production.
Courteney was born with propionic acidaemia, a rare disorder in which vital enzymes are missing.
Management of methylmalonic acidaemia by combined liver-kidney transplantation.
Jack, who lived with his family in Harperley Gardens near Stanley, County Durham, was born with the rare genetic disorder methylmalonic acidaemia.
2]) of more than 50 mmHg; and (iv) significant respiratory acidaemia.