Psiachou-Leonard E, Paterakis G, Stefanaki K, Mikraki-Christou V, Haidas S: Cerebellar granulocytic sarcoma in an infant with CD56+ acute monoblastic leukemia
ALL ALL (B) 4 ALL (T) 7 AML ApML, (AML with t[15;17][q22;q12] [PML/ RARA] and variants) 2 Acute myeloblastic leukemia, with 11q23 (MLL) abnormalities 4 AML, minimally differentiated 1 AML, without maturation 4 Acute myelomonocytic leukemia 6 Acute monoblastic leukemia
1 Acute erythroid leukemia 1 Biphenotypic acute leukemia 2 Abbreviations: ALL, acute lymphoblastic leukemia/lymphoma;ALL (B), precursor B-lymphoblastic leukemia/lymphoma;ALL (T), precursor T-lymphoblastic leukemia/lymphoma; AML, acute myeloid leukemia; ApML, acute promyelocytic leukemia;MLL, myeloid/lymphoid or mixed-lineage leukemia gene;PML, promyelocytic leukemia gene; RARA, retinoic acid receptor, alpha gene.
Thanks to a bone marrow donation when she was 1 year old, Abigail, who suffered from acute monoblastic leukemia
, is able to do all of this and more.
The patient's presenting symptom was a pigmented skin nodule that, although common for cases of acute monoblastic leukemia, is peculiar for CMML.
Skin infiltration by leukemic cells, known as leukemia cutis, is a frequent feature of acute monoblastic leukemia but is rare in CMML; only 12 cases of leukemia cutis in CMM L have been reported.
Leukemia cutis is not uncommon in blood monocytic dyscrasias, the most characteristic being the plum-colored nodules of acute monoblastic leukemia.
The second case of an 18-year-old male who had acute monoblastic leukemia associated with MS was reported by Lee et al.
A case of Marfan syndrome with acute monoblastic leukemia.