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infarction
(redirected from Acute myocardial infarction)

   Also found in: Dictionary/thesaurus, Medical, Legal, Financial, Acronyms, Wikipedia, Hutchinson 0.01 sec.
infarction, blockage of blood circulation to a localized area or organ of the body resulting in tissue death. Infarctions commonly occur in the spleen spleen, soft, purplish-red organ that lies under the diaphragm on the left side of the abdominal cavity. The spleen acts as a filter against foreign organisms that infect the bloodstream, and also filters out old red blood cells from the bloodstream and decomposes
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, kidney, lungs lungs, elastic organs used for breathing in vertebrate animals, excluding most fish, which use gills , and a few amphibian species that respire through the skin. The word is sometimes applied to the respiratory apparatus of lower animals.
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, brain brain, the supervisory center of the nervous system in all vertebrates. It also serves as the site of emotions, memory, self-awareness, and thought.

Anatomy and Function


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, and heart heart, muscular organ that pumps blood to all parts of the body. The rhythmic beating of the heart is a ceaseless activity, lasting from before birth to the end of life.
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. The acute emergency known as

myocardial infarction or heart attack is usually caused by a blockage in one of the coronary arteries that supply blood to the heart muscle. The blockage typically occurs when a blood clot (see thrombosis thrombosis (thrŏmbō`sĭs), obstruction of an artery or vein by a blood clot (thrombus).
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) lodges in an area already narrowed by arteriosclerosis arteriosclerosis (ärtĭr'ēōsklərō`sis)
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; other causes are vasospasms in the arterial walls or viral infection of the heart. Symptoms include a crushing pain in the chest radiated to either arm (more commonly the left arm), the jaw, and the neck. The pain may be experienced, particularly in women, as pain in the shoulder or stomach, instead of the chest, and in some cases there are no symptoms at all. The seriousness of the infarction is dependent upon the amount of heart muscle affected, how long the area is deprived of blood, and whether it affects the natural pacemaker of the heart, setting off arrhythmias arrhythmia (ārĭth`mēə), disturbance in the rate or rhythm of the heartbeat.
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 such as ventricular fibrillation. Death of heart muscle tissue and heart failure may result (see congestive heart failure congestive heart failure, inability of the heart to expel sufficient blood to keep pace with the metabolic demands of the body. In the healthy individual the heart can tolerate large increases of workload for a considerable length of time.
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); damage to other vital organs, including the brain, may occur if the heart is unable to pump necessary oxygen and blood to them. Confirmation of myocardial infarction is made by electrocardiography electrocardiography (ĭlĕk'trōkärdēŏg`rəfē)
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 and measurement of elevations of white blood cells and certain enzymes. Treatment of acute myocardial infarction may include first aid in the form of cardiopulmonary resuscitation cardiopulmonary resuscitation (CPR), emergency procedure used to treat victims of cardiac and respiratory arrest. CPR can be done in a hospital with drugs and special equipment or as a first-aid technique.
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 (CPR), an emergency balloon angioplasty balloon angioplasty or percutaneous transluminal coronary angioplasty, a treatment of coronary artery disease . In balloon angioplasty a balloon-tipped catheter is inserted through the skin into a blood vessel and maneuvered to the clogged portion of the artery.
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, or the administration of beta-blockers beta-blocker or beta-adrenergic blocking agent (bā`tə ăd'rənûr`jĭk)
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 and thrombolytic drugs thrombolytic drug (thrŏm'bəlĭt`ĭk) or clot-dissolving drug,
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 (clot-dissolving drugs), such as tissue plasminogen activator. The healing of an infarction occurs through replacement of the dead tissue by scar tissue.

See also coronary artery disease coronary artery disease, condition that results when the coronary arteries are narrowed or occluded, most commonly by atherosclerotic deposits of fibrous and fatty tissue.
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infarction [in′färk·shən]
(medicine)
Condition or process leading to the development of an infarct.


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The National Heart Foundation of Australia (NHFA) will partner with nurses to develop and implement strategies that aim to raise awareness of the warning signs of acute myocardial infarction (AMI) and the benefits of early, appropriate action in this life threatening situation.
In the United States alone, more than 7 million people suffer some form of Acute Myocardial Infarction (heart attack) annually, 6.
It does conclude that heavy physical exertion can trigger the onset of acute myocardial infarction, but "particularly in people who are habitually sedentary" (N Engl J Med 1993;329:1677-83).
 
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