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adaptor protein

   Also found in: Wikipedia 0.04 sec.
adaptor protein [ə′dap·tər ‚prō‚tēn]
(cell and molecular biology)
A specialized protein that links protein components of the signaling pathway, thereby aiding intracellular signal transduction.


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For example, rGrb14, the rat homologue of the human growth factor receptor, bound human Grb14 adaptor protein, a direct inhibitor of the activated insulin receptor (Bereziat et al.
It contains a complete Src homology region 2 (SH2) domain known to interact with the middle SH3 domain of Nck, an adaptor protein involved in tyrosine kinase-mediated signal transduction for both epidermal and vascular endothelial growth factors (50,54).
Regulation of Signal Transduction Pathways by Adaptor Proteins (HNV 98-22)
 
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