cell adhesion molecule

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cell adhesion molecule

[¦sel ad‚hē·zhən ′mäl·ə·kyül]
(cell and molecular biology)
A class of membrane proteins comprising the outer surfaces of cell membranes in the developing nervous system that is thought to be intimately involved in guiding development during embryonic life. Abbreviated CAM.
References in periodicals archive ?
Each of these conditions may be initiated by the expression of adhesion molecules, enhanced release of cytokines, chemokines, growth factors and other inflammatory mediators that promote migration and activation of inflammatory cells.
The hypothesis that increased levels of adhesion molecules and Cathepsin D affect cancerous cells moving away the primary tumor and contributes to migration of the cancerous cell and may cause remote organ metastases is defended.
Objective: To compare serum concentration of intracellular adhesion molecules i.
To assess their anti-inflammatory effects, we evaluated their ability to reduce the expression and secretion of the adhesion molecules ICAM-1 and VCAM-1 in HUVEC exposed to the proinflammatory cytokine TNF-[alpha].
The factors that dictate the balance between excitatory and inhibitory synaptic transmission are still poorly defined, but trans-synaptic interactions between adhesion molecules such as neurexins and neuroligins are thought to be important.
Tumor necrosis factor alpha (TNF-[alpha]) promotes the expression of adhesion molecules and induces endothelial dysfunction, a process that can lead to atherosclerosis.
Cardiologists mainly from Athens, Greece, address the role of biomarkers like C-reactive protein, interleukins, fibrinogen, peptides, adhesion molecules, microRNAs, and proinflammatory cytokines in early atherosclerosis, hypertension, hyperlipidemia, acute coronary syndromes, congestive heart failure, pulmonary embolism, coronary artery bypass grafting, peripheral vascular disease, cardiorenal syndrome, coronary artery disease, heart failure, cardiac arrhythmias, and antiplatelet treatment, as well as the role of genetics and genomics.
These results suggest that GRAPE polyphenols may potentiate vasorelaxation and reduce BP and circulating cell adhesion molecules, resulting in improvements in vascular function.
5) investigated the levels of soluble endothelial adhesion molecules (CAMs) and vascular cell adhesion molecule (VCAM-1) intercellular adhesion molecule-1 (ICAM-1) and E-selectin were compared between patients with poor coronary collaterals and patients with well-developed collaterals in a study published in 2004.
The effects of each intervention on a large number of adhesion molecules and chemokines that affect inflammation and relate to the development of vascular disease were evaluated.
Compared to the saturated fats in the butter, the polyunsaturated fats led to lower levels of markers of inflammation such as interleukin-6, TNF-alpha, and soluble vascular cell adhesion molecules (sVCAM).
Their topics include in vivo models for evaluating antithrombotics and thrombolytics, principle and practice in novel anticoagulant therapy, antithrombotic effects of naturally derived products on coagulation and platelet function, potential therapeutic and diagnostic implications of adhesion molecules, and the diagnosis and management of sickle cell disorders.