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cell adhesion molecule |
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cell adhesion molecule [¦sel ad‚hē·zhən ′mäl·ə·kyül] (cell and molecular biology) A class of membrane proteins comprising the outer surfaces of cell membranes in the developing nervous system that is thought to be intimately involved in guiding development during embryonic life. Abbreviated CAM. How to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit webmaster's page for free fun content. |
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The ICAMs do this by binding to other adhesion molecules on the surface of the cells that make up blood vessel walls. In healthy subjects, particle exposure with exercise reduced expression of adhesion molecules CD54 and CD18 on monocytes and CD18 and CD49d on granulocytes. Since thalidomide upregulates adhesion molecules in the bone marrow environment, it is possible that one mechanism of resistance to this medication may be the appearance of myeloma cells that are not sensitive to the increased expression of these adhesion molecules and therefore are more likely to leave the bone marrow to lodge at extramedullary sites. |
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