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affinity |
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affinity 1. similarity in structure, form, etc., between different animals, plants, or languages 2. Chem a. the tendency for two substances to combine; chemical attraction b. a measure of the tendency of a chemical reaction to take place expressed in terms of the free energy change. 3. Biology a measure of the degree of interaction between two molecules, such as an antigen and antibody or a hormone and its receptor affinity [ə′fin·əd·ē] (chemistry) The extent to which a substance or functional group can enter into a chemical reaction with a given agent. Also known as chemical affinity. (computer science) A specific relationship between data processing elements that requires one to be used with the other, where a choice might otherwise exist. (immunology) The strength of the attractive forces between an antigen and an antibody. How to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit webmaster's page for free fun content. |
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| ? Mentioned in | ? References in periodicals archive | |
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The improvement in homotypic neutralizing
antibody titer and decrease in heterotypic neutralizing antibody titer
described here is reminiscent of affinity maturation. The Platform, called ProCode, can be
configured for monoclonal antibody selection, affinity maturation and
library generation, for improving solubility and bioactivity of
biopharmaceuticals, as well as identification and characterization of
protein-protein interactions and discovery of protein drugs. XOMA's mAb platform includes
leading commercial antibody display phage libraries, hybridoma, Human
Engineering[TM], affinity maturation technologies, and a fully
integrated product development infrastructure, including cell line and
process development, preclinical and clinical functions, and
manufacturing. |
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