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affinity
(redirected from Affinity maturation)

    Also found in: Dictionary/thesaurus, Medical, Legal, Wikipedia 0.01 sec.
affinity
1. similarity in structure, form, etc., between different animals, plants, or languages
2. Chem
a. the tendency for two substances to combine; chemical attraction
b. a measure of the tendency of a chemical reaction to take place expressed in terms of the free energy change.
3. Biology a measure of the degree of interaction between two molecules, such as an antigen and antibody or a hormone and its receptor
affinity [ə′fin·əd·ē]
(chemistry)
The extent to which a substance or functional group can enter into a chemical reaction with a given agent. Also known as chemical affinity.
(computer science)
A specific relationship between data processing elements that requires one to be used with the other, where a choice might otherwise exist.
(immunology)
The strength of the attractive forces between an antigen and an antibody.
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The Xenerex system is able to take advantage of the unique in vivo cellular interactions, which occur in the human immune system that result in natural affinity maturation.
PEREGRINE INITIATES ANTIBODY GENERATION AGAINST 2 TARGETS by Biotech Business
The combination of Abgenix's high throughput selection technologyM and Abgenix's XenoMouse takes advantage of the natural in vivo affinity maturation process and the maintenance of the original heavy and light chain pairs.
Abgenix and Celltech enter technology licensing and co-development ... by BIOTECH Patent News
Researchers at Xencor applied the company's proprietary humanization and affinity maturation technologies to decrease the immunogenicity of XmAb5574 and to increase both its affinity and stability.
Xencor Presents Pre-Clinical Data for Anti-CD19 Antibody at AACR by Business Wire
 
 
 
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