Potash's African Green Monkey
Kidney cell line has been officially recognized by the United States Patent and Trademark Office as important for the production of human vaccines, making the process more efficient and cost effective.
Genest reported that in an African Green monkey
study treatment with RVX-208 resulted in a highly significant increase in the average of serum ApoA-I and HDL-C levels (57% and 92%, respectively).
In a poster entitled, "Efficacy of Intravenous Valortim(R), an Anti-toxin Monoclonal Antibody, in the Treatment of Inhalation Anthrax in the African Green Monkey
Model," investigators at USAMRIID sought to refine the AGM as a therapeutic model by assessing the efficacy of an anti-toxin monoclonal antibody.
An African green monkey
polyomavirus, also known as monkey B-lymphotropic papovavirus, or LPV, was isolated >30 years ago (15) from a lymphoblastoid cell line derived from the African green monkey
AGM is so remarkably different from the human AIDS viruses indicates that the human viruses cannot have originated from African green monkeys
in recent times, as had been predicted by many people.
Max Essex of the Harvard School of Public Health in Boston, who heated the team that discovered the virus as well as a similar strain in African green monkeys
, says the virus may be a "missing link" between the monkey and human viruses.
Human coronavirus (strain OC43) in different amounts was grown in African green monkey
kidney cells and thereafter potential antiviral therapies ("the test compounds") were added.
In the study, AVI's NeuGene third-generation antisense compounds were delivered to pig and African green monkey
kidney cells in cell culture.
COS cells are a derivative of the African green monkey
kidney fibroblast cell line CV-1, which is highly susceptible to SARS-CoV.
Rudel's African green monkey
study and Volcano Therapeutics' state-of-the-art IVUS technology- -present a truly unique opportunity for us to accelerate the development of our HDL Therapy platform.
Interestingly, a significant piece of the monkey virus, simian immunodeficiency virus -- African green monkey
strain (SIVagm) -- was also found in the subject's HIV viral DNA.
In one instance, the discovery of SV40 in rhesus macaque kidney cultures (15) soon led to the adoption of cynomolgus macaque and later African green monkey
(AGM) kidneys as the preferred substrate for polio vaccines.