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African Swine Fever
(redirected from African swine fever virus)

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African swine fever [′af·ri·kən ′swīn ‚fēv·ər]
(veterinary medicine)

African Swine Fever 

(Latin, Pestis Africana suum), an acute viral infection involving the reticulo-endothelial system. This disease was first observed among the swine in South Africa by Hutchen in 1903. African swine fever occurs in Africa, Italy, Spain, and Portugal. Under natural conditions, domesticated and wild swine of all ages are subject to African swine fever. Natural infection occurs through contact between healthy swine and the sick swine and virus carriers. The infection is spread through feed, pasture grounds, and means of transport contaminated by the sick swine.

The use of unsanitized wastes from cafeterias, restaurants, and slaughterhouses in the swines’ feed also contributes to the spread of infection. Insects, birds and beasts of prey, and dogs may be carriers of the virus. The incubation period is two to five days. The disease proceeds either instantaneously or acutely and chronically. In the first case, the animals die suddenly, without showing symptoms; in the second case, their temperature increases to 42.5°C, coughing and shortness of breath develops, appetite declines, nausea and paralysis occur, blood appears in wastes, the skin on ears and snout turns blue, and the animal becomes extremely weak.

No cure has been devised. On account of the highly dangerous nature of the disease and its ability to spread very rapidly, preventive measures have been centered on strict isolation of those animals suspected of the disease. When African swine fever appears, all swine on a farm are killed. The bodies are destroyed, and the pigsties and other equipment are disinfected. The introduction of new swine on the farm is permitted only one year after the disease has been liquidated.

REFERENCE

Kovalenko, Ia. R. Afrikanskaia chuma svinei. Moscow, 1965.


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The ten extended articles here follow suit in their descriptions of research in foot-and-mouth disease viruses, the molecular biology of pestiviruses, arteriviruses, coronavirus replication and interaction with the host, hendra and nipah virus, the molecular mechanisms of pathogenesis and host range in avian influenza, molecular dissection of the bluetongue virus, molecular biology of porcine circoviruses, molecular biology of animal herpesviruses, and the African swine fever virus.
00 In this multi-author work, Mettenleiter and Sobrino have compiled 10 chapters that describe what is currently known about the molecular biology of some of the most interesting viruses of veterinary importance, from the tiny circovirus of pigs (1,800 nt of single-stranded DNA) to the highly complex African swine fever virus ([approximately equal to] 200,000 nt pairs of double-stranded DNA).
 
 
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