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sleeping sickness
(redirected from African trypanosomaiasis)

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sleeping sickness: see encephalitis encephalitis , general term used to describe a diffuse inflammation of the brain and spinal cord, usually of viral origin, often transmitted by mosquitoes, in contrast to a bacterial infection of the meninges (membrane surrounding the brain and spinal cord), known as
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; trypanosomiasis trypanosomiasis , infectious disease caused by a protozoan organism, the trypanosome, which exists as a parasite in the blood of a number of vertebrate hosts. The three variations of the disease that predominate in humans are transmitted by an insect vector.
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sleeping sickness

Protozoal disease transmitted by the bite of the tsetse fly. Two forms, caused by different species of the genus Trypanosoma, occur in separate regions in Africa. The parasite enters the bloodstream and invades the lymph nodes and spleen, which become swollen, soft, and tender. Irregular fever and delayed pain sensation develop. In the Rhodesian form, the patient soon dies of massive toxemia. The Gambian type progresses to brain and spinal cord invasion, causing severe headache, mental and physical fatigue, spastic or flaccid paralysis, chorea, and profound sleepiness, followed over two or three years by emaciation, coma, and death. Some patients develop a tolerance but still carry the trypanosomes. The earlier drug treatment begins, the greater the chance of recovery. Sleeping sickness is still prevalent in parts of Africa despite efforts to control it.


sleeping sickness
1. an African disease caused by infection with protozoans of the genus Trypanosoma, characterized by fever, wasting, and sluggishness
2. an epidemic viral form of encephalitis characterized by extreme drowsiness

sleeping sickness [′slēp·iŋ ‚sik·nəs]


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