macular degeneration

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Related to Age-related macular degeneration: glaucoma, diabetic retinopathy

macular degeneration,

eye disorder causing loss of central vision. The affected area, the macula, lies at the back of the retina and is the part that produces the sharpest vision. The most serious visual impairment occurs when abnormal blood vessels form and leak serous fluid or bleed into the tissue of the macula, ultimately producing scar tissue. Peripheral (side) vision is unaffected. Onset may be acute with hemorrhage but usually is gradually progressive. Although some vision is retained, the ability to read, recognize faces, and drive a motor vehicle is greatly reduced. The condition is painless.

Macular degeneration is a major cause of vision impairment among elderly people. Although its underlying cause is unknown, it sometimes appears to run in families. Serious macular degeneraton, if diagnosed early, may have its progress stemmed by laser or photodynamic (cold laser and drug) treatment that closes leaking vessels. Antiangiogenic drugs, which inhibit the formation of new blood vessels, can be injected into the eye to stop degeneration and in some cases even improve vision. Sudden change in vision in someone over age 50 thus requires immediate medical attention.


See H. Grunwald, Twilight: Losing Sight, Gaining Insight (1999).

References in periodicals archive ?
Chapter 3 provides an overview of the leading age-related macular degeneration deals since 2010.
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Fore Pharma's latest report 'Global Age-related Macular Degeneration Drug Pipeline Capsule - 2012 Update' provides most up-to-date information on key Research and Development activities (R&D) in the global Age-related Macular Degeneration market.
What happens in age-related macular degeneration is that the retinal pigmented epithelial or RPE cells, which are essential to nourishing the retinal cells, are damaged by oxidative stress," said Herbert Weissbach, Ph.
Participants with any visual impairment, those with cataracts, and those with age-related macular degeneration were all more likely to die during the study period than those without these conditions.
They conclude that the variant boosts risk threefold and estimate that it could account for roughly half of all age-related macular degeneration cases.
Age-related macular degeneration (AMD) is the leading cause of irreversible vision loss in people over 65 in the United States.
com/research/2l4pbn/special_report_th) has announced the addition of Decision Resources, Inc's new report "Special Report: Thought-Leader Opinion on the Current and Future Landscape of the Age-Related Macular Degeneration Market" to their offering.
based company producing ophthalmic nutraceuticals, has had the ideal formulated product to combat Age-Related Macular Degeneration (AMD) since 2003.
In 4,500 adults aged 60 to 80, higher total dietary omega-3 fatty acid intake decreased the risk of developing neovascular (wet) age-related macular degeneration.
People with the eye disease called age-related macular degeneration must often contend with a blank or fuzzy spot at the very focus of their vision.
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