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agonist
(redirected from Agonists)

    Also found in: Dictionary/thesaurus, Medical, Wikipedia 0.01 sec.
agonist [′ag·ə‚nist]
(biochemistry)
A chemical substance that can combine with a cell receptor and cause a reaction or create an active site.
(physiology)
A contracting muscle that is resisted or counteracted by another muscle, called an antagonist, with which it is paired.
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Evidence that PPAR-[alpha] activation is a necessary and sufficient cause of rodent hepato-carcinogenesis supports PPAR-[alpha] activation as the sole mode of action (MOA) for these agents, and evidence that humans are relatively insensitive to this MOA have led some agencies to conclude that PPAR-[alpha] agonists do not contribute to human carcinogensis.
The PPAR-[alpha] activation MOA hypothesis revisited by Environmental Health Perspectives
We suggest that use of ERbeta agonists will be a useful addition in treatment of breast cancer, which, at present, is only aimed at inhibition of ERalpha.
Estrogen receptors alfa (ERalpha) and beta (ERbeta) differentially ... by Life Extension
Dopamine agonists are a class of drugs that are commonly used to treat Parkinson's disease, and some times restless legs syndrome.
Parkinson's disease medication may trigger compulsive gambling, ... by Asian News International
 
 
 
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