Aldolase

aldolase [′al·də‚lās]

(biochemistry)

An enzyme in anaerobic glycolysis that catalyzes the cleavage of fructose 1,6-diphosphate to glyceraldehyde 3-phosphate; used also in the reverse reaction.

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Aldolase 

an enzyme; one of the lyases, which split and synthesize carbon bonds (—C—C—). Its molecular mass is 147,000–180,000; the aldolase molecule is composed of two polypeptide chains. In animals aldolase is generally found in the skeletal muscles; in plants it is found in areas where photosynthesis takes place. Aldolase condenses aldehydes; this is the derivation of the name. It is catalyzed by a reversible reaction: fructose diphosphate ⇌ 3–phosphoglycerine aldehyde + phosphodioxyacetone. In plant tissues aldolase takes part in the dark phase of photosynthesis; in animals, in the process of glycolysis, which leads to the production of such energy-rich compounds as ATP.