The osteoblastic activity was objectively measured by measuring the serum concentrations of Bone Alkaline Phosphotase
(BAP) and the Osteoclastic activity by Serum Tartarate resistant Acid Phosphotase (TRAP).
Laboratory parameters were remarkable for a mild elevation in her hepatic transaminases (alanine aminotransferase (ALT) of 106, and aspartate aminotransferase (AST) of 111) as well as an alkaline phosphotase
3-5 [micro]g of vector was incubated with 20 units of calf intestine alkaline phosphotase
(CIAP, from Amersham Pharmacia Biotech) at 37[degrees]C for 30 minutes.