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alloxan
(redirected from Alloxane)

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alloxan [ə′läk·sən]
(biochemistry)
C4H2N2O4Crystalline oxidation product of uric acid; induces diabetes experimentally by selective destruction of pancreatic beta cells. Also known as mesoxyalyurea.
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Streptozotocin (STZ), a nitrosurea derivative isolated from Streptomyces achromogenes, also destroys pancreatic [beta]-cells via the same mechanism as alloxane (Junod et al.
Therapy of diabetes mellitus using experimental animal models by Min, T.S.; Park, S.H. / Asian - Australasian Journal of Animal Sciences
 
 
 
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