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granule
(redirected from Alpha granules)

    Also found in: Dictionary/thesaurus, Medical, Wikipedia 0.01 sec.
granule, in astronomy: see photosphere photosphere, luminous, apparently opaque layer of gases that forms the visible surface of the sun or any other star. The photosphere lies between the dense interior gases and the more attenuated gases of the chromosphere.
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granule
Geology a single rock fragment in gravel, smaller than a pebble but larger than a sand grain
granule [′gran·yül]
(astronomy)
A convective cell in the solar photosphere, about 600 miles (1000 kilometers) in diameter.
(geology)
A somewhat rounded rock fragment ranging in diameter from 2 to 4 millimeters; larger than a coarse sand grain and smaller than a pebble.
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9,10) Platelet-derived growth factor and PDGFR are found in the alpha granules of platelets and in mesenchymal and epithelial cells in a variety of tissues.
Prognostic significance of CD44, platelet-derived growth factor ... by Tawfik, Ossama W.; Kramer, Brandan; Shideler, Barbara; Danley, Marsha; Kimler, Bruce F.; Holzbeierle / Archives of Pathology & Laboratory Medicine
4) PRP is thought to work via the degranulation of the alpha granules in platelets that contain a number of growth factors believed to be important in early wound healing.
Platelet-rich plasma in endoscopic sinus surgery by Rice, Dale H. / Ear, Nose and Throat Journal
Intracellular signaling processes lead to increased cytoplasmic calcium and then initiate a secretory release reaction, whereby products from the alpha granules (platelet factor 4, [beta]-thromboglobulin, thrombospondin, platelet-derived growth factor, fibrinogen, VWF) and dense granules (adenosine diphosphate [ADP], serotonin) are released into the surrounding milieu.
The laboratory diagnosis of platelet disorders: an algorithmic ... by Kottke-Marchant, Kandice; Corcoran, George / Archives of Pathology & Laboratory Medicine
 
 
 
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