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Alport's syndrome

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Alport's syndrome [′al‚pȯrts ‚sin‚drōm]
(medicine)
A very rare genetic disease of the glomeruli that results in glomerular scarring and eventual renal failure within the second or third decade of life.


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In April last year, 39-year-old James gave a kidney to his 37-year-old wife, who suffers from Alport's Syndrome, which causes kidneys to fail.
In comparing the glomerular basement abnormalities in patients with familial hereditary nephritis (Alport's syndrome) and TGBM nephropathy, Piel et al (23) in 1982 suggested the possibility that Alport's syndrome and TGBM may be variations in the spectrum of inherited abnormalities in the formation of the GBM.
Fechtner syndrome--a variant of Alport's syndrome with leukocyte inclusions and macrothrombocytopenia.
 
 
 
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