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tissue plasminogen activator
(redirected from Alteplase)

   Also found in: Dictionary/thesaurus, Medical, Wikipedia 0.01 sec.
tissue plasminogen activator [¦tish·ü plaz‚min·ə·jən ′ak·tə‚vād·ər]
(medicine)
A proteolytic enzyme that can convert plasminogen to plasmin.


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Alteplase is a tissue plasminogen activator enzyme that binds to fibrin in a thrombus and converts the plasminogen to plasmin, initiating fibrinolysis.
Patients across the town suffering an attack will now be able to get clot-busting drug Alteplase along with thrombolysis treatment at their local hospital day and night.
Ishemic stroke patients with an area of hypoperfusion larger than the area of infarct and cytotoxic damage may still benefit from alteplase 3-6 hours after stroke onset, according to a study presented at the International Stroke Conference 2008 in New Orleans.
 
 
 
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