amphotericin B

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amphotericin B

(ăm'fətĕr`ĭsĭn), antibioticantibiotic,
any of a variety of substances, usually obtained from microorganisms, that inhibit the growth of or destroy certain other microorganisms. Types of Antibiotics
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 that halts the growth of several disease-causing fungi. Discovered in 1956, it is produced by bacteria of the genus Streptomyces. It is used in lotion or ointment form to treat fungal infections of the skin and is given internally only to patients with potentially fatal fungal infections. Amphotericin B is not effective against bacterial infections.

amphotericin B

[‚am·fə′ter·ə·sən ′bē]
(microbiology)
C46H73O20N The active component of amphotericin, suitable for systemic therapy of deep or superficial mycotic infections.
References in periodicals archive ?
We are pleased to offer AmBisome as one of our first critical care products, and we look forward to introducing several more high-growth critical care products, including high-end antibiotics, in the near future.
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A dose of Fungizone was administered instead of AmBisome in six cases, leading to the two deaths in two of those.
It may be worthwhile to investigate the potential for AmBisome interference on other analyzers that use a phosphomolybdate ultraviolet assay from other manufacturers.
AmBisome is the only antifungal agent indicated for the treatment of febrile neutropenia with suspected mycotic infection.
8 million result from collaborations with corporate partners, including contract revenues for research and development projects, and royalties on product sales of AmBisome in the United States by Gilead's co-promotion partner Fujisawa Healthcare and VISTIDE in the European Union by Pharmacia & Upjohn.
In the Indian subcontinent, where VL is endemic, the WHO Leishmaniasis Expert Committee recommends single-dose AmBisome as the safest, most effective treatment for the disease.
An agent discovered by US company Gilead Sciences, AmBisome is indicated for the treatment of infections caused by Aspergillus, Candida and Cryptococcus as well as febrile neutropenia with possible fungal infection.
Since the product's European introduction in 1990, Gilead has successfully grown the market for Ambisome throughout the world.
ATLANTA -- AmBiLoad Study Evaluated Optimum Use of AmBisome for Patients With Life-Threatening Infections
Fujisawa submitted a supplemental New Drug Application (sNDA) for AmBisome in July 1999 seeking a label expansion for the additional indication.
It sells five drugs, Truvada, Viread and Emtriva, for HIV treatment; AmBisome, for fungal infections; and Hepsera for chronic hepatitis B infection.