Ames test


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Ames test

[′āmz ‚test]
(analytical chemistry)
A bioassay that uses a set of histidine auxotrophic mutants of Salmonella typhimurium for detecting mutagenic and possibly carcinogenic compounds.
References in periodicals archive ?
Comparison of the Ames II and traditional Ames test responses with respect to mutagenicity, strain specificities, need for metabolism and correlation with rodent carcinogenicity.
Rat fed with milk cultured with Enterococcus faecium IS-27526 significantly decreased fecal as well as urinary mutagenicity of rats as measured by the Ames test (Tables 3 and 4).
Using the Ames test, EGCG was added to DNA samples challenged
It includes practical approaches on how to perform the tests and to interpret the results and describes a stepwise testing strategy, starting with the Ames test.
The routine use by the chemical industry of the Ames test and related short-term tests for mutagenesis as part of new product development has undoubtedly prevented the release of carcinogenic chemicals into the environment.
Now known as the Ames test, it is still used by researchers.