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Ames test |
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Ames test [′āmz ‚test] (analytical chemistry) A bioassay that uses a set of histidine auxotrophic mutants ofSalmonella typhimuriumfor detecting mutagenic and possibly carcinogenic compounds. How to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit webmaster's page for free fun content. |
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| , inventor of the Ames test for mutagenicity and
professor of biochemistry and molecular biology at U. APM was not genotoxic in the following tests: dominant lethal
mutation assay in rats, host-mediated assay in rats and mice, in vivo
cytogenetic assay in rats, and the Ames test (Kotsonis and Hjelle 1996). Commonly found in feces, 7-OHIQ was identified during the 1980s as
a direct-acting mutagen in the Ames test, a bacterial assay used to
screen for potential carciongens. |
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