Ames test

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Ames test

[′āmz ‚test]
(analytical chemistry)
A bioassay that uses a set of histidine auxotrophic mutants of Salmonella typhimurium for detecting mutagenic and possibly carcinogenic compounds.
References in periodicals archive ?
While the statistical evaluation of the results of the Ames test is under discussion (Kim and Margolin, 1999; Mortelmans and Zeiger, 2000) and depends also from the historical data achieved in the individual testing site, the responsible laboratory considered a test item showing a positive response, if the number of revertants was significantly increased (p < 0.
The purpose of this research was to determine the mutagenic potential of the Cauca River waters in the urban zone of the city of Cali by using the well known Ames test, and also identify and quantify some of the most dangerous pollutants such as pesticides and heavy metals.
The S9 enzymatic activator is used in the Ames test to simulate the effect of organic compounds in the liver of mammals.