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(organic chemistry)
The preparation of amines.
A process in which the amino group (=NH2) is introduced into organic molecules.



a method of introducting the amino group NH2 into various organic compounds. A typical example of amination is the action of alkali metal amides on heterocyclic bases. Thus, the interaction of pyridine with sodium amide at temperatures of about 200°C leads to the formation of α-aminopyridine (A. E. Chichibabin and O. A. Zeide, 1914):

C5H5N + NaNH2 → C5H4N(NH2) + NaH

Passing benzene vapor with ammonia through an incandescent tube results in a very low output of aniline:

C6H6 + NH3 → C6H5NH2 + H2

References in periodicals archive ?
A family of new chiral C2 symmetric amido-oxazolinate ligands, bridged by three different linkers, have been synthesized via a modular Buchwald-Hartwig amination reaction.
Criteria for inclusion was as follows; patients with non infected closed mandibular angle fractures, which were displaced on clinical ex- amination and panoramic radiographs.
Alanine, the [alpha]-amino acid analog of the [alpha]-keto acid pyruvate, is most commonly produced by the reductive amination of pyruvate via alanine transaminase.
One concern is that the current method requires a relatively large number of steps before LC-MS/ MS: (a) digestion of proteins in the DBS with a protease; (b) ion exchange enrichment of glycosaminoglycans and desalting; (c) digestion of carbohydrate polymers with bacterial lyases; (e) reductive amination tagging with isotopic aniline; f) addition of synthetic standards; and (g) MS/MS coupled with UHPLC.
Later, pre paration of the Fmoc-protected aza-arginine precursor was accomplished according to Scheme 1A, using reductive amination of 3-([N.
2013) Ex amination of visual information as a mediator of external focus benefits.
Amination the cyanohydrin with ammonia or other amines causes production of alpha-amino-nitriles which are widely used for synthesizing the alpha amino acids.
Included are stereoselective oxidation and reduction methods; stereoselective additions; cyclizations; metatheses and different types of rearrangements; asymmetric transition-metal-catalyzed, organocatalyzed, and biocatalytic reactions; methods for the formation of carbon-heteroatom and heteroatom-heteroatom bonds like asymmetric hydroamination and reduction amination, carboamination and alkylative cyclization, cycloadditions with carbon-heteroatom bond formation, and stereoselective halogenations; and methods for the formation of carbon-sulfur and carbon-phosphorus bonds and asymmetric sulfoxidation.
Firstly, carbon nanotubes were functionalized through five successive stages, including purification, oxidation, amination, melamination and thiolation.
Consumer groups such as the NRDC, the Environmental Working Group, and others applauded the FDA proposal but noted that the ex amination of the ingredient has already been 30 years in the making.
Keerthi Devi, "Direct one-pot reductive amination of aldehydes with nitroarenes in a domino fashion: catalysis by gum-acacia-stabilized palladium nanoparticles," Journal of Organic Chemistry, vol.
5 Gastrointestinal contrast ex- amination may help to detect the conjunction of the gastrointestinal tract.