Amination

amination [‚am·ə′nā·shən]

(organic chemistry)

The preparation of amines.

A process in which the amino group (=NH₂) is introduced into organic molecules.

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Amination 

a method of introducting the amino group NH₂ into various organic compounds. A typical example of amination is the action of alkali metal amides on heterocyclic bases. Thus, the interaction of pyridine with sodium amide at temperatures of about 200°C leads to the formation of α-aminopyridine (A. E. Chichibabin and O. A. Zeide, 1914):

C₅H₅N + NaNH₂ → C₅H₄N(NH₂) + NaH

Passing benzene vapor with ammonia through an incandescent tube results in a very low output of aniline:

C₆H₆ + NH₃ → C₆H₅NH₂ + H₂