amphetamine

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Related to Amphetamines: Benzodiazepines, opiates, Hallucinogens

amphetamine

(ămfĕt`əmēn), any one of a group of drugs that are powerful central nervous system stimulantsstimulant,
any substance that causes an increase in activity in various parts of the nervous system or directly increases muscle activity. Cerebral, or psychic, stimulants act on the central nervous system and provide a temporary sense of alertness and well-being as well as
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. Amphetamines have stimulating effects opposite to the effects of depressantsdepressant,
any one of various substances that diminish functional activity, usually by depressing the nervous system. Barbiturates, sedatives, alcohol, and meprobamate are all depressants. Depressants have various modes of action and effects.
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 such as alcohol, narcoticsnarcotic,
any of a number of substances that have a depressant effect on the nervous system. The chief narcotic drugs are opium, its constituents morphine and codeine, and the morphine derivative heroin.

See also drug addiction and drug abuse.
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, and barbituratesbarbiturate
, any one of a group of drugs that act as depressants on the central nervous system. High doses depress both nerve and muscle activity and inhibit oxygen consumption in the tissues. In low doses barbiturates act as sedatives, i.e.
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. They raise the blood pressure by causing the body to release epinephrineepinephrine
, hormone important to the body's metabolism, also known as adrenaline. Epinephrine, a catecholamine, together with norepinephrine, is secreted principally by the medulla of the adrenal gland.
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, postpone the need for sleep, and can reverse, partially and temporarily, the effects of fatigue. Amphetamines enhance mental alertness and the ability to concentrate, and also cause wakefulness, euphoria, and talkativeness. Benzedrine is the trade name for the drug amphetamine; dextroamphetamine is marketed as Dexedrine. Methamphetamine, a potent stimulant marketed as Desoxyn, is the most rapidly acting amphetamine. They are available by prescription for limited uses; illegal sources include stolen or diverted supplies or clandestine laboratories.

Uses

Prescription amphetamines have been used for short periods of time in weight-control programs to suppress appetite and to treat narcolepsy. They were used as vasoconstrictors in inhalant therapy to shrink nasal mucous membranes in such conditions as nasal allergies and asthma; now such inhalants have been banned because of their toxicity. For unknown reasons, amphetamines have a paradoxically calming effect on some hyperactive children, but the use of these drugs to treat such children has been controversial.

Amphetamine Abuse

Popularly known as bennies, crank, speed, pep pills, wakeups, or uppers, amphetamines are addictive and easily abused: users can become psychologically dependent on the drugs and, developing a tolerance for them, can require increasingly large doses (see drug addiction and drug abusedrug addiction and drug abuse,
chronic or habitual use of any chemical substance to alter states of body or mind for other than medically warranted purposes. Traditional definitions of addiction, with their criteria of physical dependence and withdrawal (and often an underlying
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). When the drugs wear off, a long period of sleep ensues, often followed by hunger and depression, which can lead to further use of amphetamines. Amphetamine addiction has been common among such diverse groups as truck drivers, students, and athletes, who have used the drugs for increased energy, alertness, or endurance. Methamphetamine, made from ephedrineephedrine
, drug derived from plants of the genus Ephedra (see Pinophyta), most commonly used to prevent mild or moderate attacks of bronchial asthma. Unlike epinephrine, to which it is chemically similar, ephedrine is slow to take effect and of mild potency and long
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 and other chemicals in clandestine laboratories in the the United States or Mexico, experienced a resurgence in use in the United States beginning the mid-1990s, and its abuse also has increased worldwide. Amphetamines are inhaled, taken orally, or injected; as with other injected drugs, needle sharing increases the risk of contracting the AIDSAIDS
or acquired immunodeficiency syndrome,
fatal disease caused by a rapidly mutating retrovirus that attacks the immune system and leaves the victim vulnerable to infections, malignancies, and neurological disorders. It was first recognized as a disease in 1981.
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 virus. One form of methamphetamine, "ice," is smoked. For law enforcement purposes in the United States, most amphetamines are grouped with such drugs as cocaine and morphine because of the similarity in their effects, medical usefulness, and high potential for abuse.

Side Effects

Amphetamines can produce severe systemic effects, including cardiac irregularities and gastric disturbances. Chronic use often results in insomnia, hyperactivity, irritability, and aggressive behavior. Addiction can result in psychosis or death from overexhaustion or cardiac arrest. Amphetamine-induced psychosis often mimics schizophrenia, with paranoia and hallucinations.

amphetamine

[‚am·fed·ə‚mēn]
(pharmacology)
C6H5CH2CHNHCH3 A volatile, colorless liquid used as a central nervous system stimulant.

amphetamine

a synthetic colourless volatile liquid used medicinally as the white crystalline sulphate, mainly for its stimulant action on the central nervous system, although it also stimulates the sympathetic nervous system. It can have unpleasant or dangerous side effects and drug dependence can occur; 1-phenyl-2-aminopropane. Formula: C6H5CH2CH(NH2)CH3
References in periodicals archive ?
9 million 50 mg doses of amphetamines - or around one dose for every person living in the North East.
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The latter greatly enhances the former's psychoactive properties, making the codrug a powerful amphetamine, according to scientists from the Scripps Research Institute in La Jolla, California, who published their findings in the journal Nature on Wednesday.
In June 2017, long-acting, triple-bead mixed amphetamine salt (MAS) was FDA-approved under the brand name Mydayis for the once-daily treatment of ADHD in adolescents (age [greater than or equal to]13) and adults (Table l).
On April 27, a man called Carl Currie was caught with 20 kilos of amphetamines in 10 packages in a Renault Megane on the M4.
Mr Roberts asked if she remembered asking him to contact a dealer to get amphetamine on the way to school that morning, and arguing with him because the dealer was not there because she wanted more speed.
Llewellyn was jailed for four years and four months after admitting supplying amphetamines and possessing cocaine with intent to supply.
He was convicted of conspiracy to supply cocaine and amphetamines for his part in the plot and admitted a failure to surrender.
A Lebanese official says Beirut airport authorities have foiled one of the country's largest drug smuggling attempts, seizing two tons of amphetamine Captagon pills before they were loaded onto the private plane of a Saudi prince.
In a cupboard near the entrance door they found a glass jar containing a quantity of amphetamine in plastic bags suggestive of street deals worth around PS790.
For the second boarding on Dec 16, the boarding party nabbed amphetamines worth $5.
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