anaphylatoxin

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anaphylatoxin

[¦an·ə‚fil·ə′täk·sən]
(immunology)
The vasodilator principal, a toxic substance released by tissues of sensitized animals when antigen and antibody react.
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References in periodicals archive ?
CCX168 is a highly potent and very selective compound that specifically targets the receptor for the anaphylotoxin designated C5a, a component of the body's complement system and a potent driver of the inflammatory response associated with ANCA-associated vasculitis and other autoimmune disease.
A role for the C3a anaphylotoxin receptor in the effector phase of asthma.
The surface of a mast cell has a number of different receptors, including those for IgE antibodies and the complement fragments C3a and C5a--the anaphylotoxins (see Figure 1, p22).