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androgen
(redirected from Androgen insensitivity)

   Also found in: Dictionary/thesaurus, Medical, Wikipedia, Hutchinson 0.01 sec.
androgen (ăn`drəjən): see testosterone testosterone (tĕstŏs`tərōn), principal androgen, or male sex hormone .
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androgen

Any of a group of hormones that mainly influence the development of the male reproductive system. The main and most active androgen is testosterone, produced by cells in the testes. Androgens produced in smaller quantities, mainly by the adrenal gland but also by the testes, support the functions of testosterone. Androgens cause the normal changes of puberty in boys' bodies and then influence sperm-cell formation, sexual interest and behaviour, and male pattern baldness. Females produce trace quantities of androgens, mostly in the adrenal glands, as well as in the ovaries.


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The study sample of 37 participants includes ten persons with complete androgen insensitivity (CAIS), five with partial androgen insensitivity (PALS), four women with CAH, two women with progestogen-induced clitoromegaly, one each of Klinefelter's syndrome in a male and Turner's syndrome in a female, six miscellaneous patients including gonadal dysgenesis, micropenis, true hermaphroditism, and at least two with hypospadias, plus eight for whom the diagnosis is unknown.
ISNA News, redesigned and rejuvenated this month after a move from its beginnings in San Francisco to a new home in Michigan, is published by the Intersex Society of North America, whose board of directors includes representatives of the Androgen Insensitivity Support Group, the International Gay and Lesbian Human Rights Commission, the Intersex Society, and the Michigan State University Dept.
Zucker examined a number of known diagnoses for intersex children, including androgen insensitivity syndrome, congenital adrenal hyperplasia, 5 alpha-reductas deficiency, partial androgen insensitivity syndrome, micropenis syndrome, penile agensis (the penis fails to differentiate), cloacal exstrophy, and penis ablatio.
 
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