Anfinsen, Christian Boehmer

Anfinsen, Christian Boehmer,

1916–95, American biochemist, b. Monessen, Pa., Ph.D. Harvard Medical School, 1943. He spent the early years of his career in brief research and fellowship positions at various medical institutions and agencies. In 1963 he joined the National Institute of Arthritis and Metabolic Diseases (NIAMD), where he headed the chemical biology laboratory until 1981. From 1983 until he died, he was a professor at Johns Hopkins. Anfinsen shared the 1972 Nobel Prize in Chemistry with Stanford MooreMoore, Stanford,
1913–82, American biochemist, b. Chicago, Ph.D. Univ. of Wisconsin, Madison, 1938. Moore joined the faculty at the Rockefeller Institute for Medical Research (now Rockefeller Univ.) in New York in 1939 and remained there until his death in 1982.
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 and William SteinStein, William Howard,
1911–80, American biochemist, b. New York City, Ph.D. Columbia, 1937. Stein was a professor at the Rockefeller Institute for Medical Research (now Rockefeller Univ.) from 1937 until he retired in 1971.
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 for his work on the enzyme ribonuclease, which catalyzes the hydrolysis of ribonucleic acid (RNA) into smaller components. He is credited with illuminating the connection between the molecular structure of the ribonuclease molecule and the biological function of this enzyme.

Anfinsen, Christian Boehmer

 

Born Mar. 26, 1916, in Monessen, Pa. American biochemist. Member of the National Academy of Sciences of the USA and of the American Academy of Arts and Sciences (1958); foreign member of the Royal Danish Society (1964).

Anfinsen received degrees from the University of Pennsylvania (1939) and from Harvard University. He was a fellow at the Carlsberg Laboratory in Copenhagen in 1940, and from 1944 to 1950 he conducted research at the Harvard Medical School, where he was a professor of biochemistry in 1962 and 1963. From 1950 to 1962, Anfinsen directed the laboratory of cellular physiology and metabolism at the National Heart Institute in Bethesda, Md. In 1963 he became director of the laboratory of chemical biology at the National Institute for Arthritis and Metabolic Diseases. His principal works have been concerned with establishing the structure of ribonuclease.

In 1972, Anfinsen shared the Nobel Prize in chemistry with S. Moore and W. Stein.

WORKS

In Russian translation:
Molekuliarnye osnovy evoliutsii. Moscow, 1962.

REFERENCE

Serebrovskaia, K. B., and B. D. Komissarov. “Kristian Bemer Anfinsen.” Zhurnal Vses. khim. ob-va, 1975, vol. 20, no. 6.
“Anfinsen, C. B.” In McGraw-Hill Modern Men of Science, vol. 2. New York, 1968.