The ANK1 gene encodes Ankyrins
, which are a family of proteins that link membrane proteins to the cytoskeleton (Chorzalska et al.
Ankyrins are especially likely to be of relevance as they might be involved in the recognition of and protection from host phagocytosis (Liu et al.
Functional diversity of ankyrin repeats in microbial proteins.
Ankyrins also play critical roles for ion channel regulation in other excitable cells, such as neurons and heart cells called cardiomyocytes,"
The new mechanism involves a protein called ankyrin and appears to regulate specialized pancreatic cells and insulin secretion
G (ANKG), which is encoded by the ANK3 gene, is crucial for the stability of the neuronal membrane [5, 6] and facilitates the connection between axons and ribbon synapses.