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antimetabolite |
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antimetabolite: see metabolite metabolite, organic compound that is a starting material in, an intermediate in, or an end product of metabolism . Starting materials are substances, usually small and of simple structure, absorbed by the organism as food. ..... Click the link for more information. . antimetaboliteSubstance that competes with, replaces, or inhibits a specific compound within a cell, whose functioning is thereby disrupted. Because its structure resembles the compound's, it is taken up by the cell, but it does not react in the same way with the enzyme that acts on the usual compound. It may inhibit the enzyme or be converted into an aberrant chemical. Many antimetabolites are useful in treating disease, including sulfa drugs, which disrupt bacterial but not human metabolism for bacterial diseases, and others (e.g., methotrexate, 5-fluorouracil) for various cancers. |
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2026: Phase I and pharmacokinetic trial of oral administration of CYC682, a novel 2' deoxycytidine type anti-metabolite pro-drug, in patients with advanced solid tumors or lymphoma. Applying OculusGen simply adds a step to the traditional trabeculectomy technique, and improves results by eliminating anti-metabolite side effects. By applying OculusGen, anti-metabolism drug need not be prescribed and this will prevent those side effects of anti-metabolites. |
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