antinuclear antibody

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antinuclear antibody

[¦an·tē¦nü·klē·ər ′an·tə‚bäd·ē]
(immunology)
Antibody to deoxyribonucleic acid, ribonucleic acid, histone, or nonhistone proteins found in the serum of individuals with certain autoimmune diseases. Abbreviated ANA.
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Anti-nuclear antibody was positive at a titer of 1:1000, and anti-Jo-1 antibody was negative.
Studies for c-ANCA, anti-proteinase 3 (PR3), anti-GBM, cryoglobulins, complement levels, anti-nuclear antibody, rheumatoid factor, hepatitis A, B, and C, and creatinine kinase were normal.
The joint project combines NanoValent's hybrid polymerized liposomal nanoparticle (HPLN), which can be loaded with chemotherapeutic substances for safer drug delivery, and NanoSmart's patented anti-nuclear antibody (ANA), a platform technology that targets areas of necrosis present in all solid tumors.
Image Navigator[R] is a system that will organize and simplify your Anti-Nuclear Antibody testing.
Typically, detection of autoantibodies directed against extractable nuclear antigen's (ENA) is a second-round set of analyses following a reactive anti-nuclear antibody (ANA) test.
Anti-nuclear antibody was absent, rheumatoid factor was negative, complement 3 (83 mg/dl, normal: 77-195) and complement 4 (25 mg/dl, normal: 7-40) levels were normal.
Only a few cases of the prozone phenomenon for anti-nuclear antibody detection have been described.
Indicators of nonspecific inflammation and autoimmune activity, such as C-reactive protein, rheumatoid factor, and anti-nuclear antibody titers were within normal limits.
With the suspicion of a systemic vasculitic disease, autoimmune serology including serum rheumatoid factor, anti-nuclear antibody and anti-neutrophil cytoplasmic antibodies (ANCA) was studied and all were negative.
However, P-ANCA staining is also seen with antibodies to other neutrophil enzymes and with anti-nuclear antibodies (a neutrophil-specific anti-nuclear antibody or wrong reading because of the presence of anti-nuclear antibodies).