4) Anticholinergic agents
affect the human body by inhibiting specific receptors, which is supposed to suppress the permanent or sudden urge to urinate.
In a randomized, placebo-controlled, crossover trial, 21 cognitively intact elderly persons were given doses of placebo or Artane (trihexyphenidyl), a muscarinic anticholinergic agent
with documented adverse effects on diverse cognitive functions.
If approved, mirabegron will offer patients and physicians the first new oral mechanism of action in OAB treatment since the launch of the first anticholinergic agent
30 years ago.
This XOPENEX/ipratropium formulation should provide us with an exciting franchise management opportunity that has the potential to broaden our established XOPENEX patient base by providing increased convenience to levalbuterol patients who require the addition of an anticholinergic agent
," said Adrian Adams, President and Chief Executive Officer of Sepracor.
Specifically they will provide further insight into the individual component doses, compare clinical activity to that of a short-acting anticholinergic agent
and assess any cardiovascular effects.
Glycopyrrolate, an anticholinergic agent
, also is approved as an adjunctive therapy in the treatment of peptic ulcers.
Clinical stage programs include: NH001, a dopaminergic agent to help post traumatic brain injury patients to emerge from a coma, vegetative or minimally consciousness state; NH004, an anticholinergic agent
in a convenient intra-orally dissolving film to help treat motor neuron patients who suffer from sialorrhea (drooling); and NH02D, a novel mechanism compound to accelerate the rehabilitation outcomes of stroke patients who remain with chronic motor and cognitive disabilities.
Dicyclomine HCl is a generic version of Hoechst Marion Roussel's, Bentyl(R), an antispasmodic and anticholinergic agent
and is fully interchangeable with Bentyl(R).
SAN DIEGO, May 23 /PRNewswire/ -- According to study data presented today at the International Conference of the American Thoracic Society, patients with chronic obstructive pulmonary disease (COPD) experienced significant improvements in health-related quality-of-life measures after nine months of treatment with tiotropium bromide inhalation powder (SPIRIVA(R) HandiHaler(R)), a once-daily inhaled anticholinergic agent
An antispasmodic and anticholinergic agent
, the Lannett version of Bentyl(R) relieves muscle spasm of the gastrointestinal tract and is indicated for the treatment of functional bowel/irritable bowel syndrome.
This increase," Lannett President Barry Weisberg states, "is attributable primarily to the Company's continued success in the introduction of Dicyclomine Hydrochloride USP, 10 mg Capsules, a generic version of the Marion Merrell Dow antispasmodic and anticholinergic agent
Bentyl(R), launched in the first quarter Fiscal 1995.
Scopolamine hydrobromide, an anticholinergic agent
, is approved by the Food and Drug Administration for the prevention of nausea and vomiting associated with motion sickness and recovery from anesthesia and surgery.