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antidiuretic hormone

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antidiuretic hormone (ăn'tēdīyrĕt`ĭk), polypeptide hormone secreted by the posterior pituitary gland pituitary gland, small oval endocrine gland that lies at the base of the brain. It is sometimes called the master gland of the body because all the other endocrine glands depend on its secretions for stimulation (see endocrine system).
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. Its principal action is to regulate the amount of water excreted by the kidneys. Antidiuretic hormone (ADH), known also as vasopressin, causes the kidneys to resorb water directly from the renal tubules, thus concentrating the salts and waste products in the liquid, which will eventually become urine. ADH secretion by the pituitary is regulated by neural connections from the hypothalamus, which is believed to monitor either the volume of blood passing through it or the concentration of water in the blood. Dehydration or body stress will raise ADH secretion and water will be retained. Alcohol inhibits ADH secretion. Failure of the pituitary to produce ADH results in diabetes insipidus. In pharmacological doses ADH acts as a vasoconstrictor. The structure and chemical synthesis of ADH was announced (1953) by Nobel laureate Vincent Du Vigneaud and others.
antidiuretic hormone [¦an·tē‚dī·yə¦red·ik ′hȯr‚mōn]
(biochemistry)


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Alcohol causes the brain, specifically the pituitary gland, to clock vasopressin, the body''s natural antidiuretic hormone.
When there is a large amount of urine produced at night by the kidney, a synthetic antidiuretic hormone medication called desmopressin can be prescribed to decrease the amount of urine produced.
The increase of % TBW could be the result of different mechanisms: Protein catabolism with hypoproteinemic edema, increased protein synthesis with increased plasma volume (PV), increase in PV due to sodium retention, based on an increased aldosterone concentration and impairment of the antidiuretic hormone and dehydration and impaired renal function due to skeletal muscle damage.
 
 
 
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