Resistance without Prior Exposure to Antifungal Drugs
To enhance the efficacy of antifungal drugs
, their combined use with the EOs is one of the promising strategies (Giordani et al.
The company's initial priorities are the development of biofilm inhibitors, antifungal drugs
, and a portfolio of technologies to enhance the production of microbially produced drugs and other metabolites.
Current Market Situations of China's Major Antifungal Drug
Some of the restraints to market's growth are growing resistance to antifungal drugs
, limitations with antifungal drugs
, presence of generics and government regulations in pharmaceutical industry.
The researchers say that their findings attain significance because only one new class of antifungal drugs
has been introduced in the last two decades, and they must be administered intravenously.
susceptibility testing of clinical isolates demonstrated relatively high MICs to all antifungal drugs
tested (Table 2).
resistance is quickly becoming a major problem in the expanding population of immunocompromised persons.
Although CAI (carboxamide-amino-imidazole) was originally developed as an antifungal drug
by the Merck Institute for Therapeutic Research, Liotta's team discovered that it also trips up traveling tumor cells.
The product is designed to target the site of infection directly with a novel formulation of amphotericin B, a broad spectrum, "gold-standard" antifungal drug
The new FDA approved antifungal drug
product is the 6th approved antibacterial or antifungal medicine designated as a Qualified Infectious Disease Product (QIDP).
susceptibilities of oral Candida dubliniensis isolates from human immunodeficiency virus (HIV)-infected and non-HIV-infected subjects and generation of stable fluconazole-resistant derivatives in vitro.