Antifungal

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Antifungal

 

a medicinal preparation used to treat such fungal diseases as dermatomycoses, onychomycoses, and candidiasis. Externally, antifungals are applied locally to the focus of the infection in the form of ointments, solutions, and other medicines. They are used to remove skin epidermis, hair, and nails infected by a fungus (salicylic and lactic acid preparations). Other antifungals suppress fungal growth (Amicazol [Asterol Dihydrochloride], Zincundan, and Nitrofungin). Systemic antifungals either kill fungi or inhibit their reproduction when taken orally (griseofulvin, nystatin, Levorin) or when injected intravenously (amphotericin B).

References in periodicals archive ?
Clinical, cellular, and molecular factors that contribute to antifungal drug resistance.
18 Moreover, the antifungal susceptibility pattern of isolated Aspergillus species in the current study depicted increasing resistance against commonly used antifungal drugs such as amphotericin B and azoles, which are in accordance with a previous relevant study conducted on A.
A better approach is to fabricate such acrylic dentures which may act as DRDs (Drug releasing devices) from which antifungal drugs elute and inhibit microbial growth.
fumigatus were subjected to in-vitro antifungal drug sensitivity against Amphotericin-B, Clotrimazole, Nystatin and Fluconazole.
We retrospectively reviewed electronic medical records for demographic, clinical, and laboratory data for the day of candidemia (defined as day of blood collection for culture), and we reviewed pharmacy records and clinical notes for previous use of antifungal drugs and cumulative doses.
9) Thus, in vivo response of the antifungal drug has earned importance and therefore, was the basis of this study.
Of great concern to the clinical and healthcare communities is the rise in fungal infections, which are resistant to conventional antifungal drugs, as well as increasing reports of resistance development in patients toward antifungal agents.
This study can be of clinical significance, as incorporation of antifungal drug ketoconazole sensitivity disc into GC Soft shows good inhibition and can be recommended for clinical use.
Although the metabolism of sphingolipids is similar among fungi and animals, certain enzymes involved in sphingolipids synthesis are considered potential antifungal drug targets due to specific differences with their mammalian counterparts (1).
It's good news for patients with severe asthma to have an existing antifungal drug recognized as having benefits for asthma patients with fungal allergy," notes one researcher.