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The goal was to learn whether use of acute antimigraine medication to abort attacks predisposes patients over time to what has been termed "migraine chroni-fication," or the conversion of episodic migraine into even more disabling and burdensome chronic headache, which in this study was defined as any type of headache occurring 15 or more days per month.
A further correlation between these transcription factors and migraine pain arises from the recent observation that triptans, widely used antimigraine drugs.
Side effects may include serotonin syndrome, particularly when lorcaserin is taken with therapies that increase serotonin levels or activate serotonin receptors, such as antimigraine drugs or antidepressants.
Triptans and NSAIDs, two of the most frequently used antimigraine agents, target different aspects of the vascular and inflammatory processes that are believed to underlie migraine.
Although the triptan drug class is crowded and increasingly generic, opportunity exists for alternative acute antimigraine therapies that offer unique mechanisms of action or improved efficacy and/or safety profiles," said Decision Resources Senior Director Bethany A.
Boston--The investigational antimigraine drug drugtelcagepant may provide relief for patients with acute moderate to severe migraine who do not respond to treatment with triptan agents, according to results from the first phase III clinical trial.
Before 2003, when the International Classification of Headache Disorders was updated, the definition of MOH (formerly called drug-induced headache), did not cover all available agents, especially not modern antimigraine drugs such as trip-tans, Dr.
ALGRX 2872 consists of a triptan antimigraine drug in a novel formulation.
patient-level claims data, among approved acute antimigraine products assessed, oral triptans are the most commonly prescribed therapies used by newly diagnosed patients across the first three lines of therapy within two years of diagnosis.
Although the results are not as good as those achieved with standard antimigraine drugs, a noninvasive, nondrug treatment could avoid the side effects of migraine medications, Dr.
Partial relief can usually be obtained through such other medications as NSAIDs, antidepressants, antiepileptic drugs, and antimigraine drugs.