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antisense strand

   Also found in: Dictionary/thesaurus, Medical, Wikipedia 0.01 sec.
antisense strand [¦an·tē′sens ‚strand]
(cell and molecular biology)
The strand of a double-stranded deoxyribonucleic acid molecule from which ribonucleic acid is transcribed. Also known as anticoding strand.


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The thermo-stability bias at the 5' end of the antisense strand: Since it is desirable to have only the antisense strand incorporated into the RISC complex, lowering the thermo-stability at the 5' end of the antisense strand can promote helicase unwind siRNA duplexes from this end [17,20,21].
In this technique, a complementary strand of RNA, the antisense strand, binds to part of a cell's normal, single-stranded RNA.
5' C A U G 3' mRNA 3' G U A C 5' Antisense RNA The second strand is called the antisense strand because its sequence of nucleotides is the reverse complement of message sense.
 
 
 
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