Antisyphilitic


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Antisyphilitic

 

a medicinal preparation used in the treatment of syphilis. Antisyphilitics that have a specific effect on the pathogen of syphilis (Treponema pallidum) include some antibiotics (penicillin, Ecmonovocillin, Bicillin, and erythromycin), organic arsenicals (Novarsenol, mi-arsenol, and osarsol), salts of heavy metals (Biiochinol, Bismoverol, corrosive mercuric chloride, mercuric cyanide, and red mercuric iodide), and iodine alkalies (sodium and potassium iodides). Antisyphilitics kill the pathogens of the disease, cause the manifestations of primary and secondary syphilis to disappear, and change the serological reactions from positive to negative. The following are applied externally: an ointment containing 5 to 10 percent white precipitate, penicillin ointment, 1- to 10-percent emulsion of synthomycin, and corrosive mercuric chloride solutions. Specific and nonspecific therapy are usually combined to improve the therapeutic effect. The administration and dosage of antisyphilitic preparations are determined in accordance with specific treatment regimens.