antithrombin

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Related to Antithrombin III: antithrombin III test, protein C

antithrombin

[‚an·tē′thräm·bən]
(biochemistry)
A substance in blood plasma that inactivates thrombin.
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References in periodicals archive ?
Clotting factor abnormalities, including elevated antithrombin III and antiphospholipid antibody, were detected in three of nine patients in that study.
Eighteen patients consented to a prospective hypercoagulability evaluation that included assays for protein C, protein S, APC resistance, factor V Leiden mutation, anticardiolipin antibodies, antineutrophil cytoplasmic antibodies (ANCA), rheumatoid factor, antithrombin III, anti-smooth muscle antibody, and lupus anticoagulant panel.
When GTC won regulatory approval to sell ATryn in 2009, it was after a hearing in which New Mexico lawyer Karen Janes spoke about her hope for a treatment that could help her daughter, who inherited an antithrombin III deficiency.
Cryoglobulin, p-antineutrophilic cytoplasmic antibody, c-antineutrophilic cytoplasmic antibody, antinuclear antibody, rheumatoid factor, and antithrombin III, were all negative.
Protein C, protein S, and antithrombin III in acute ocular occlusive diseases.
Fondaparinux works with antithrombin III to inhibit activated factor X, a key part of the clotting pathway.
The claims of this new patent relate to a method of treating subjects having an antithrombin III deficiency or inflammation with the administration of recombinant antithrombin III produced in the mammary gland of a non-human mammal.
Potentially adverse cardiovascular effects of HRT include increases in C-reactive protein, factor VII, and activated protein C resistance; decreased antithrombin III levels have also been seen.
Antithrombin III deficiency, protein C deficiency; and protein S deficiency for example, are extremely rare in patients without a family history of venous thromboembolism.
Patients with a thrombophilia but no prior or acute thrombosis need not be treated, except for those with antithrombin III deficiency.
Other biomarkers measured include levels of LDL cholesterol, HDL cholesterol, lipoprotein, erythrocytes, leukocytes, fibrinogen, antithrombin III, and osteocalcin.
Xa inhibitor, direct thrombin inhibitors, antithrombin III, activated protein C (aPC) and inhibitors of platelet aggregation via the ADP receptor, glycoprotein IIb/IIIa (GP IIb/IIIa) or other mechanisms.