Aotus


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Aotus

 

a genus of mammals of the superfamily Platyrrhini. The genus comprises the single species Aotus trivirgatus (douroucouli). The body length measures 24–37 cm, and the tail length 30–40 cm; the weight is 0.6–1 kg. The upper part of the body and the tail are predominantly brownish gray; the face and throat are light. The eyes are very large owing to the animal’s nocturnal habits. The douroucouli is found in the mountain forests of northeastern South America. It feeds on fruits and leaves of trees, on insects, on spiders, on birds, and sometimes, on small mammals. The female bears a single offspring once a year.

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Immunogenicity and protective efficacy of recombinant vaccine based on the receptorbinding domain of the Plasmodium vivax duffy binding protein in Aotus monkeys.
Studies on the Indochina I/CDC strain of Plasmodium falciparum in Colombian and Bolivian Aotus monkeys and different anophelines.
GTC's technology produced a version of the MSP-1 (Merozoite Surface Protein 1) protein that successfully protected Aotus nancymai monkeys in a preclinical vaccine study conducted by the National Institute of Allergy and Infectious Diseases (NIAID).