apoptosis

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apoptosis

[‚ā·pō′tō·səs]
(cell and molecular biology)
Death of cells triggered by extracellular signals or genetically programmed events, carried out by processes within the cell, and characterized by systemic breakdown of cellular constituents, in particular chromosomal deoxyribonucleic acid; may be involved in normal development and aging, or may serve to eliminate defective or damaged cells. Also known as programmed cell death.
References in periodicals archive ?
05 was taken to be significant and the apoptotic results were shown as percentage of cells.
Metformin protect against PTZ-induced apoptotic neurodegeneration: Mitochondrial changes occurs after the activation of caspases pathway.
Pearson's linear correlation analysis was used for correlation between peak apoptotic activity levels at 72nd hours of reperfusion and peak CK-MB ortroponin levels, glycosylated haemoglobin (HbA1c).
Also the apoptotic hepatocytes expressing Caspase 3 increased significantly in a proportionate fashion (p<0.
8) did not find any statistically significant difference between CIN-I and CIN-II as well as between CIN-II and CIN-III groups in terms of apoptotic and mitotic cell counts.
Evaluation of the formation of apoptotic nuclei in resistant cells
Determination of the type of apoptotic pathway induced by caspase-3 and -9 assays
Morphological detection of apoptotic cells was determined using Hoechst33342 staining.
The biopsy specimens from patients with celiac disease and controls were subjected to immunohistochemical (IHC) staining for markers of the intrinsic apoptotic pathway (apoptosis-inducing factor [AIF], p53, and H2AX), markers of common pathway (cleaved caspase-3 [CC3] and M30 cytodeath), and markers of apoptotic inhibitors (XIAP and Bcl2).
In a mouse model of pneumocytis pneumonia, although the infection was localised to the lungs, significant changes in apoptotic proteins in splenic lymphocytes were found, suggesting that an apparently localised pulmonary infection can also stimulate lymphocyte apoptosis at extra-pulmonary sites (25).
Histopathological hyperthermic damage assessment subgroups were categorized as follows: healthy cells, necrotic cells, HSP 27 cells, HSP 70 cells, apoptotic cells.
The D-Pop kit allows scientists to fractionate apoptotic bodies from cell-free fluids in minutes, and can be used to process high volumes of cell-free fluids.

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